Structures of Mefenamic Acid Metabolites from Human Urine.
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چکیده
منابع مشابه
Spectrophotometric Determination of Mefenamic Acid Excreted as Free Drug in Urine of Human Beings
Urinary excretion of free mefenamic acid was investigated in 16 healthy human volunteers, eight males and eight females, following the oral administration of 500mg tablet of mefenamic acid. Urine samples were collected at pre-determined schedule and drug concentration was determined by spectrophotometric method. The total recovery of free mefenamic acid was 1.526 ± 0.128 and 1.193 ± 0.112% in m...
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Volatile constituents of 30 urines from 10 adults have been studied by gas chromatography, and two also by mass spectrometry. The sample was prepared by extracting urine with ethyl ether, distilling the extract at low temperature under reduced pressure, and concentrating the distillate to a few microliters. High-efficiency capillary columns, 150 m X 0.5 mm i.d., provide the resolution necessary...
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Wholegrain cereals are reported to promote beneficial health effects. Wholegrain wheat and rye are almost exclusive sources of alkylresorcinols, and intact alkylresorcinols together with their plasma and urinary metabolites, 3-(3,5-dihydroxyphenyl)-1-propanoic acid (DHPPA) and 3,5-dihydroxybenzoic acid (DHBA), have been proposed as biomarkers of the intake of these foods in humans. The pharmaco...
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*To whom all correspondence should be addressed. he quality of a solid pharmaceutical preparation is influenced by primary micromeritic characteristics such as the shape and size of drug crystals, especially when large amounts of poorly soluble drugs are formulated. To improve the dissolution rate of poorly soluble drugs, fine crystals are preferred over large crystals because they provide a gr...
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ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 1993
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.16.811